source : hormone.org
Calcitonin | Hormone Health Network
When it comes to hormone health, the thyroid gland has a huge role to play. It produces and controls numerous hormones that affect many aspects of daily life. Calcitonin is one of those critical hormones.
Calcitonin is a hormone that the C-cells in the thyroid gland produce and release. It opposes the action of the parathyroid hormone, helping to regulate the blood’s calcium and phosphate levels.
How does calcitonin work?
Calcitonin works to control calcium and potassium levels. It does this by inhibiting the activity of the osteoclasts, the cells that break down bone. When the osteoclasts break down bone tissue, the calcium enters the bloodstream. By preventing the breakdown of bone, calcitonin lessens the amount of calcium in the blood. The hormone also seems to decrease the amount of calcium the kidneys can re-absorb, lowering levels further.
Secretion of this hormone is controlled directly by the blood’s calcium levels. When the levels start to increase, the body responds with increased calcitonin levels. When calcium levels drop, so do calcitonin levels.
What can go wrong with calcitonin?
Calcitonin is a unique hormone, because its importance is not well known. While doctors know what it does, they do not understand why we have it, and few symptoms occur if levels are high or low. The body appears to function normally, even with high or low levels of this thyroid hormone. In fact, patients who have had their thyroids removed will have virtually no calcitonin levels, but they show no resulting symptoms.
Sometimes high calcitonin levels can point to a rare type of medullary thyroid cancer. This cancer, which starts in the C-cells, can be connected to multiple endocrine neoplasia type 2b and multiple endocrine neoplasia type 2a. However, the calcitonin levels do not cause the cancer.
Questions to ask your doctor
If you have blood work done that indicates high or low calcitonin levels, you may wish to talk to your doctor about the problem to determine if there is an underlying cause or issue with your thyroid. Specifically, if your levels are high, consider asking why or requesting further testing to rule out cancer. Otherwise, high or low calcitonin levels have little affect on your overall health. Still, if you have concerns, talk to an endocrinologist to ensure you are getting support from a hormone specialist. Find an endocrinologist in your area to get started.
What is calcitonin? – Quora – Calcitonin is a 32 amino acid peptide hormone secreted by parafollicular cells of the thyroid gland in humans, and in many other animals in the ultimopharyngeal body. It acts to reduce blood calcium, opposing the effects of parathyroid hormone. Calcitonin has been found in fish, reptiles, birds…Calcitonin, whose importance in human metabolism is likely quite limited, is mentioned at the end of the chapter. Their effect upon the metabolism of proteins is complex. Thyroid hormones stimulate the synthesis of some of the proteins (Na+/K+-ATPase, respiratory chain enzymes), but at the same…Calcitonin is a hormone that is produced and released by the C-cells of the thyroid gland. Its biological function in humans is to have a relatively However, the importance of this role in humans is unclear, as patients who have very low or very high levels of calcitonin show no adverse effects.
4. Thyroid Hormones, Calcitonin and Hormones of the Parathyroid… – Peptides Related to Calcitonin. Calcitonin in the Central Nervous System. The accepted nomenclature became calcitonin (CT), which described a new hormone of thyroid gland origin that FIGURE 2-1 Comparison of the effects of surgical thyroparathyroidectomy with parathyroidectomy by…Calcitonin is one of the most critical hormones, controlling calcium and potassium levels. Learn how this hormone affects many aspects of your health and how It opposes the action of the parathyroid hormone, helping to regulate the blood's calcium and phosphate levels. How does calcitonin work?Calcitonin-salmon (Miacalcin) is a man-made version of the hormone calcitonin. Calcitonin-salmon is prescribed to treat osteoporosis (postmenopause), Paget's disease of the bone, and hypercalcemia. Side effects, drug interactions, warnings and precautions, and efficacy during pregnancy information…
Calcitonin | You and Your Hormones from the Society for Endocrinology – Different hormones have different effects on the shape of the body. Some of these hormones work quickly to start or stop a process and some will continually work over a long period of time to So, now you may have come to know about the various hormones and their functions in the human body.Calcitonin, a peptide hormone secreted by the thyroid gland, tends to decrease plasma calcium concentration and, in general, has effects opposite These cells constitute only about 0.1 per cent of the human thyroid gland and are the remnants of the ultimo-brachial glands of lower animals such as…Calcitonin inhibits osteoclasts, but its effects are transitory. Calcitonin is a 32-amino-acid peptide hormone made by the clear or C cells of the thyroid gland. C cells (also called parafollicular cells) are derived from neural crest cells of the fifth branchial pouch, which in humans migrate into the evolving…